近期发表代表性论文: 1.Evaluation of in vitro toxicity of polymeric micelles to human endothelial cells under different conditions, Chemico-Biological Interactions, 2016.12.23,263:47-54. Fang Liu.Haikang Huang, Yu Gong, Juan Li, *Xuefei Zhang and *Yi Cao 2.Prodrug Micelles Based on Norbornene-Functional Poly(lactide)s Backbone for Redox-Responsive Release of Paclitaxel. Australian journal of Chemistry, 2016, 69, 1140-1148. Ji Wang, Jing Yan, Huicong Zhou, Haikang Huang, *Xuefei Zhang and *Haoyu Tang 3.Synthesis of pH-sensitive, water-soluble Paclitaxel prodrugs based on norbornene-functional polylactide by copper-free click chemistry. International Journal of Polymeric Materials and Polymer Biomaterials 2016, 65 789-796, Ji Wang, Huicong Zhou, Qixuan Zheng, Jing Yan, Pei Liu, Guanghua Li, *Xuefei Zhang and *Haoyu Tang 4.Water-Soluble Poly(e-caprolactone)-Paclitaxel Prodrugs Toward an Efficient Drug Delivery System. Australian journal of Chemistry, 2015, 68,1136-1143. Ji Wang, Huanjiao Sun, Deshan Li, Jie Yuan, *Xuefei Zhang, and *Haoyu Tang 5.(Methoxy-Poly(ethylene glycol)-block-Poly(ε-caprolactone) Bearing Pendant Aldehyde Groups as pH-Responsive Drug Delivery Carrier). Australian Journal of Chemistry 2013, 66(12), 1576-1583. Gejun Ma, Deshan Li, Ji Wang,*Xuefei Zhang, *Haoyu Tang 6.pH-Triggered Charge-Reversal Polypeptide Nanoparticles for Cisplatin Delivery: Preparation and In Vitro Evaluation. BIOMACROMOLECULES, 2013,14(6), 2023-2032, Huang Yue, *Tang, Zhaohui, *Zhang, Xuefei, Yu Haiyang, Sun Hai, Pang Xuan, Chen Xuesi 7.Synthesis and characterization of a novel biodegradable amphiphilic MPEG-dendritic block copolymer containing (glycolic acid)-alt-(lactic acid) oligomer and glycerol. Journal of Controlled Release, 2011,152: e264-e266. Jianwei Jiang, Li Zhang, Miao Wu, Xuefei Zhang* 8.Synthesis and Characterization of a Well-Defined Amphiphilic Block Copolymer and Its Paclitaxel Prodrug from Methoxy Poly(ethylene glycol) and Oligomer of Glycolic Acid. Journal of Applied Polymer Science, 2011, 758-766. Li Zhang, Jinyan Fu, Zhixiang Xia, Ping Wu, Xuefei Zhang* 9.Synthesis and Characterization of a Novel Biodegradable Amphiphilic Dendritic Polyether-ester. Australian Journal of Chemistry. 2012, 65, 545–551, Jin peng Xiao, Hong Wang, Qiang Yi, Gejun Ma, Xue fei Zhang* 10.A new approach for synthesis of the comb-shaped poly (e-caprolactone) brushes on the surface of nano-hydroxyapatite by combination of ATRP and ROP, Journal of Colloid and Interface Science, 2010, 352: 36-42. Liang Zeng, Haibo Wang, Guoxin Fu , Jianwei Jiang, Xuefei Zhang* 11.Fabrication and characterization of nanocomposites with high-impact polystyrene and hydroxyapatite with well-defined polystyrene via ATRP. Journal of Reinforced Plastics and Composites , 2011, 30 , 1445-1453. Guoxin Fu, Zhixiang Xia, Jianwei Jiang, Bo Jing, Xuefei Zhang * 12.Preparation and Characterization of Nanocomposites based on Poly (ε-caprolactone) and the Surface Grafted Nanohydroxyapatite with the Comb-shaped Poly (ε-caprolactone) Brushes, Polymers and Polymer Composites, 2012, 20,463-469 . Guoxin Fu, Liang Zeng, Jianwei Jiang, Zhixiang Xia, Bo Jing, Xuefei Zhang * 近期申请专利: 1.张雪飞,黄海康,一种具有量子点示踪功能的两亲性聚合物抗肿瘤前药及其制备方法,中国发明专利,申请号:201610567036.7 2.张雪飞,柳培,一种具有靶向和示踪功能的抗肿瘤高分子键合药及其制备方法,中国发明专利,申请号:201610564588.2 3.张雪飞,赵碧云,一种具有多药协同作用的抗肿瘤高分子键合药及其制备方法,中国发明专利,申请号:201610566950.X 4.张雪飞,黄海康,王骥,一种可生物降解且具有 pH 响应性的抗肿瘤高分子键合药及其制备方法,中国发明专利,申请号:201510278554.2 5.张雪飞,李德珊,一种以聚乙二醇-b-聚ε-己内酯为载体的pH响应型抗肿瘤前药及其制备方法,中国发明专利,申请号:201510278922.3 6.张雪飞,王骥,一种具有氧化还原响应性可降解水溶性抗肿瘤聚合物前药及其制备方法,中国发明专利,申请号:201510627046.0 7.张雪飞,王骥,王海康,一种水溶性可降解的抗肿瘤前药及其制备方法,中国发明专利,申请号:201410815834.8 8.张雪飞,麻戈军,含侧羟基或含侧羧基官能团的聚丙交酯及其制备方法 ,中国发明专利,专利号:ZL:201310181259.6 (已授权)。 9.张雪飞,麻戈军,一种聚ε-己内酯负载的抗肿瘤前药及其制备方法,中国发明专利,专利号:ZL:201310179788.2(已授权)。 10.张雪飞,麻戈军,一种聚丙交酯负载的前药及其制备方法 ,中国发明专利,专利号:ZL: 201310181055.2(已授权)。 11.张雪飞,傅金燕,钟冠群,张海良,一种结构精确的新型两亲性聚合物为载体的抗肿瘤前药及合成方法。中国发明专利,专利号:ZL 200810143664.8(已授权)。 12.张雪飞,段谆谆,钟冠群,张海良,一种新型两亲性超支化聚酯为载体的抗肿瘤前药及制备方法。中国发明专利,专利号:ZL 200810143665.2(已授权)。 13.张雪飞,曾亮,一种基于纳米羟基磷灰石的生物活性材料及制备方法。中国发明专利,专利号:ZL 200910227126.1(已授权)。 14.张雪飞,付军,张力,一种基于甘油为支化单元的新型两亲性聚酯型树枝状大分子为载体的抗肿瘤前药及制备方法。中国发明专利,申请号:200910043525.2。 |