陈冬花

职称：副教授

性别：女

职务：

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电子邮箱：1106933632@qq.com

工作学习经历

主讲课程

分析化学、近代实验技术等

研究方向 

生命活性物质和环境有害物质的化学传感分析新方法、新技术研究

主要学术成果 

发表论文：

1. Jiao Luo, Hongyan Tan, Bin Yang, Donghua Chen*, Junjie Fei*. A Mesoporous Silica-based Probe with a Molecularly Imprinted Polymer Recognition and Mn:ZnS QDs@Rhodamine B Ratiometric Fluorescence Sensing Strategy for the Analysis of 4-Nitrophenol. Analytical Methods, 2022, 14: 3881-3889

2. Hongyan Tan, Hong Zhou, Donghua Chen*. A Peroxyoxalate Chemiluminescence Recovery System Based on the Interaction of N-doped Graphene Oxide Nanosheets and an Oligopeptide for Ultra-sensitive and Selective Copper(II) Ion Detection. Analytical Methods, 2022, 14: 1897-1903

3. Wenxin Wang, Zhiqing Wang, Zhike Tan, Guojiang Mao, Donghua Chen, Chunyan Li*. A Nitrobenzoxadiazole-based Near-infrared Fluorescent Probe for the Specific Imaging of H₂S in Inflammatory and Tumor Mice. Analyst, 2022, 147: 2712-2717

4. Yinping Deng, Jun Du, Donghua Chen, Guojiang Mao, Bin Yang*, Yin Zhang, Zhu Su, Hanfen Cai. Junction Toehold: A Novel Approach for Flexible DNA Strand Displacement and Bioassay. Sensors & Actuators: B. Chemical, 2021, 347: 130645

5. Donghua Chen*, Siming Wen, Rulin Peng, Qingsong Gong, Junjie Fei*, Zhuo Fu, Chao Weng, Minna Liu. A Triple Signal Amplification Method for Chemiluminescent Detection of the Cancer Marker microRNA-21. Microchimica Acta, 2019, 186: 410

6. Donghua Chen*, Rulin Peng, Hong Zhou, Hui Liu. Sensitive Determination of 4-Nitrophenol Based on its Enhancement of a Peroxyoxalate Chemiluminescence System Containing Graphene Oxide Quantum Dots and Fluorescein, Microchimica Acta, 2016, 183: 1699-1704

7.  Xijuan Tan, Zhuming Wang, Donghua Chen, Kai Luo, Xunyu Xiong, Zhenghua Song*. Study on the Interaction of Catalase with Pesticides by Flow Injection Chemiluminescence and Molecular Docking, Chemosphere, 2014, 108: 26-32

8. Judong You, Jiangman Liu, Donghua Chen, Zhenghua Song*. Determination of Matrine in Medicine and Bio-Fluids Based on Inhibition of Luminol–Myoglobin Chemuluminescence. Journal of Analytical Chemistry, 2014, 69(1): 17-21

9. Jie Guo, Kai Luo, Donghua Chen, Xijuan Tan, Zhenghua Song*. A Rapid and Sensitive Method for the Determination of Dibutylphthalate in Wine by Flow Injection Chemiluminescence Analysis, Journal of Food Composition and Analysis, 2013, 31(2): 226-231

10. Donghua Chen, Zhenghua Song*, Hairu Lv. Assay of Picogram Level Isocarbophos Residue on Tangerines and Oranges with Luminol–Albumin Chemiluminescence System, Food Chemistry, 2012, 135(4): 2549-2553

11. Donghua Chen, Zhuming Wang, Yun Zhang, Xunyu Xiong, Zhenghua Song*. Study on the Interaction Behavior of Catalase with Cephalosporins by Chemiluminescence with Flow Injection Analysis, Analytical Methods, 2012, 4(6): 1485-1487

12. Min Wu, Donghua Chen, Zhenghua Song*. Study on the Luminescence Behavior of Sulfobutylether-Β-Cyclodextrin with Risperidone and its Analytical Application, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2012, 96: 1-9

13. Jingjing Zhang, Min Wu, Donghua Chen, Zhenghua Song*. Ultrasensitive Determination of Melamine in Milk Products and Biological Fluids by Luminol–Hydrogen Peroxide Chemiluminescence. Journal of Food Composition and Analysis, 2011, 24(7): 1038-1042

14. Donghua Chen, Zhenghua Song*. In Vitro Monitoring Picogram Level Risperidone in Human Urine with Luminol–Lysozyme Flow Injection Chemiluminescence, Microchimica Acta, 2010, 171(3-4): 437-440

15.  Donghua Chen, Zhenghua Song*, Qiaoli Yue. Sensitive Assay for Picogram Levels of Sudan I in Chilli Foodstuffs by Flow Injection Chemiluminescence. Analytical Methods, 2010, 2(9): 1316-1319

16.  Zhuming Wang, Donghua Chen, Xin Gao, Zhenghua Song*. Subpicogram Determination of Melamine in Milk Products Using a Luminol–Myoglobin Chemiluminescence System, Journal of Agricultural and Food Chemistry, 2009, 57(9): 3464-3469

科研项目：

1. 国家自然科学基金青年项目：控释型比色分析体系构建及硝基苯酚类污染物现场快速监测研究(22106131)，起止年月：2022-01至 2024-12。主持

2. 湖南省自然科学基金青年项目：基于介孔二氧化硅的化学发光信号放大传感体系构建及乳腺癌相关miRNA精确检测研究(2019JJ50623)，起止年月：2019-01至2021-12。主持

3. 国家自然科学基金青年项目：名称：可编程的核酸适配体荧光探针的构建及其在细胞膜蛋白时空分辨成像中的应用(21505113)，起止年月：2016-01至2018-12。参与

4. 湖南省教育厅一般项目：基于氧化石墨烯的化学发光信号放大体系构建及miRNA检测研究(15C1312)，起止年月：2015-01至2017-12。主持

个人简介 

陈冬花，女，汉族。2008年本科毕业于山西大同大学，获理学学士学位，同年考入西北大学化学与材料科学学院分析化学专业攻读硕士学位，2009年以硕博连读方式攻读博士学位，2013年毕业并获理学博士学位，2017年进入金沙9170登录线路化学博士后科研流动站工作。以第一作者或通讯作者身份在Food Chemistry、Microchimica Acta及Analytical Methods 等SCI期刊发表多篇论文。先后主持或参与国家自然科学基金项目、湖南省自然科学基金项目及湖南省教育厅一般项目等。